Cynosure PinPointe Footlaser Nail Fungus

The first clinically proven laser device for onychomycosis,
or nail fungus. Cynosure PinPointe Footlaser Nail Fungus is
turning feet that suffer from unsightly nail fungus into
happy feet for men and women the world over.
Cynosure Pinpointe Laser• Indicated for use for
the temporary increase of clear nail in patients with
onychomycosis. e.g., dermatophytes Trichophyton rubrum and
T. mentagrophytes, and/or yeasts Candida albicans, etc.
In clinical studies, more than 70% of patients experienced
improvement after a single treatment
Poses none of the risk and harmful side effects of
oral anti-fungal medications
Convenient in-office procedure that typically takes less than
10 minutes per foot to perform

PinPointe FootLaser
Improve patient throughput, increase practice revenue.
The innovative technology and sleek, stylish design of
the PinPointe FootLaser enhances the patient appeal of
any practice.

The PinPointe FootLaser received U.S.
Food and Drug Administration clearance in October 2010 for
the treatment of Onychomycosis.
The system also is cleared for marketing in Australia,
Canada and the European Union.

“The treatment of Onychomycosis represents an
emerging opportunity for light-based technology,”
said Cynosure President and
Chief Executive Officer Michael Davin.
“We are acquiring the worldwide exclusive rights to
a system that we believe is considered the leading solution for
treating this indication.
With almost 100,000 PinPointe FootLaser treatments
performed worldwide to date, our distribution agreement with
NuvoLase immediately gives us a leadership position in
the market.”

The distribution agreement gives Cynosure rights to
distribute both current and future NuvoLase products for
the treatment of Onychomycosis.
In North America, Cynosure plans to sell the
PinPointe FootLaser through a new dedicated podiatry
direct sales team supported by the Company’s existing
direct sales force.
The American Podiatric Medical Association estimates that
there are approximately 15,000 podiatrists currently
practicing in the United States. In Europe,
the system will initially be marketed through
Cynosure’s direct subsidiaries.
Cynosure expects to launch the product in
additional markets in the Asia Pacific region and
through select international distributors in the future.

“We believe Cynosure’s expansive distribution network will
help drive the adoption of the PinPointe FootLaser system on a
global basis,” said NuvoLase President and Chief Executive
Officer Steven P. Duddy. “The expertise Cynosure has
demonstrated in developing and marketing laser- and
light-based treatments for minimally invasive and
non-invasive aesthetic applications will be crucial in
gaining market share for this fast-growing indication.”

Onychomycosis is a condition marked by the growth of
fungus under the nail. Fungi feed on keratin,
the protein that makes up the hard surface of the toenails.
The infected nail often turns darker in color,
and debris may accumulate under the nail.
As the infection continues, the nail either may
crumble gradually and fall off or thicken.

Cynosure PinPointe Footlaser Nail Fungus uses laser light to
kill the fungus that lives in and under the nail without causing
damage to the nail or the surrounding skin.
The treatment typically takes 20 minutes with
no downtime. In a 12-Month Multi-Site Retrospective Study
conducted on more than 250 sequential patients,
71.4% of patients experienced continuous improvement in
clear nail area after a single treatment.
By contrast, the current standard of care for
Onychomycosis – oral drugs and topical medications – are
estimated to be only between 30-50% effective in
treating the indication and have the potential for
significant side effects.