Agilent 6410B Triple Quadrupole LC/MS System

Specifications:
MS/MS sensitivity and repeatability: 0.5 pg of reserpine injected on column, ESI source, three concurrent MRM acquisitions, quantifying on the
transition m/z 609 to 195.
Signal-to-noise ratio >20:1, where noise = 5x RMS.
Mass resolution: Three settings (FWHM) Unit: 0.7 u; Wide: 1.2 u; Widest: 2.5 u
Mass accuracy: 0.1 u across the mass range
Mass stability: 6.5 × 106
Mass range: m/z 15–1,650
Scan rate: 5,200 u/sec
Scan modes: MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM
Minimum MRM dwell time: 5 ms with 10 MRMs
MRM transitions: 99 per time segment, thousands possible with multiple segments
Positive/negative polarity switching: Time segment dependent; Inter-segment delay of 1.5 sec
Collision cell: High-pressure, hexapole with linear acceleration
Cross-talk: None detectable

Features:
Single point of control: Single-point data system method capability with full control of Agilent 1100 and 1200 Series HPLC systems and 6410 Triple Quadrupole LC/MS
Time programming:
Positive/negative polarity switching in a time segment
Scan and SIM or MRM (plus other modes of data collection)
Solvent divert through calibrant delivery system valve
Possible 99-time segments with potential 99 MRMs per-time window
Wide range of ionization sources
Electrospray (ESI)
Nanospray with HPLC-Chip Cube MS interface
Atmospheric pressure chemical ionization (APCI)
Multimode source (simultaneous ESI and APCI)
Autotune: Automated optimization of ion optics and mass axis calibration
Solvent declustering: Countercurrent gas
Detector: High-energy conversion dynode and removable electron multiplier horn
Vacuum system: One triple-stage turbomolecular pump with one mechanical pump

Technical Specifications:
18.5" H x 43.5" W x 26" D (47 x 111 x 66 cm)
236.5 lbs (107.5 kg)
Line Voltage & Frequency: 200 - 240 VAC @ 50/60 Hz
Supply Circuit Rating: 15 A
Maximum power consumption: 2700

The system includes:
• Agilent 6410B QQQ with 1200/1290 HPLC
• G1379B Degasser
• G1312B Binary Pump SL
• G1367D HIP ALD SL
• Vacuum Pump
• Computer pre-loaded with software
• Keyboard, mouse and monitor